Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation
نویسندگان
چکیده
منابع مشابه
Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation.
Binding of APOBEC3G to the nucleocapsid (NC) domain of the human immunodeficiency virus (HIV) Gag polyprotein may represent a critical early step in the selective packaging of this antiretroviral factor into HIV virions. Previously, we and others have reported that this interaction is mediated by RNA. Here, we demonstrate that RNA binding by APOBEC3G is key for initiation of APOBEC3G:NC complex...
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ژورنال
عنوان ژورنال: RNA
سال: 2008
ISSN: 1355-8382
DOI: 10.1261/rna.964708